خاموش و روشن کردن همجنس گرايي در يک نوع مگس
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خاموش و روشن کردن همجنس گرايي در يک نوع مگس
Hamjensgera 2007-12-12, 05:35
لینک به منبع
قبل از اینکه راه بیفتید و بگید که داروی همجنس گرایی و دگر جنس گرایی کشف شده بدانید که "این تحقیق در مگس بوده نه انسان" !
مقاله ای آمده از دانشگاه Illinois در شیکاگو و محققی به نام David Featherstone ادعا کرده که همجنس گرایی در یک نوع مگس به وسیله تنظیم کننده سیناپسی که قبلا ناشناخته بوده کنترل میشه. محقان این پروژه ادعا کردند که با استفاده از دارو و تغییرات ژنتیکی این تنظیم کننده سیناپسی را میتوانند دست کاری کنند و همجنس گرایی را مانند یک سوئیچ در این نوع مگس خاموش و روشن کنند. همچنین این محققان ژنی را در این مگس به نام genderblind کشف
کردند که آن را به اختصار GB نام گذاشتند،
همچنین مشاهده کردند که نوعی تحول در ژن GB این مگس را دو جنس گرا میکند.
Fruit Fly Homosexuality Study
Likely To Prove Controversial
by 365Gay.com Newscenter Staff
Posted: December 10, 2007 - 8:00 am ET
(Chicago,
Illinois) While the biological basis for homosexuality remains a mystery, a
team of neurobiologists says it may be closer to an answer.
The team led by University of
Illinois at Chicago researcher David Featherstone says it has discovered that
sexual orientation in fruit flies is controlled by a previously unknown
regulator of synapse strength.
Armed with this knowledge, the researchers claim they were able to use either
genetic manipulation or drugs to turn the flies' homosexual behavior on and off
within hours.The research will appear in the January issue of Nature
Neuroscience the university said.
Featherstone, associate professor of biological sciences at UIC, and his
coworkers discovered a gene in fruit flies they called "genderblind," or GB. A
mutation in GB turns flies bisexual.Featherstone found the gene interesting
initially because it has the unusual ability to transport the neurotransmitter
glutamate out of glial cells -- cells that support and nourish nerve cells but
do not fire like neurons do. Previous work from his laboratory showed that
changing the amount of glutamate outside cells can change the strength of nerve
cell junctions, or synapses, which play a key role in human and animal behavior.
But the GB gene became even more interesting when post-doctoral researcher Yael
Grosjean noticed that all the GB mutant male flies were courting other males.
"It was very dramatic," said Featherstone. The GB mutant males, he said, treated
other males exactly the same way nonmutant male flies would treat a female. They
even attempted copulation Featherstone said. Other genes that alter sexual
orientation have been described, but most just control whether the brain
develops as genetically male or female. It's still unknown why a male brain
chooses to do male things and a female brain does female things. The discovery
of GB provided an opportunity to understand why males choose to mate with
females. "Based on our previous work, we reasoned that GB mutants might show
homosexual behavior because their glutamatergic synapses were altered in some
way," said Featherstone. Specifically, the GB mutant synapses might be stronger.
"Homosexual courtship might be sort of an 'overreaction' to sexual stimuli," he
explained. To test this, he and his colleagues genetically altered synapse
strength independent of GB, and also fed the flies drugs that can alter synapse
strength. As predicted, they were able to turn fly homosexuality on and off --
and within hours."It was amazing. I never thought we'd be able to do that sort
of thing, because sexual orientation is supposed to be hard-wired," he said.
"This fundamentally changes how we think about this behavior." Featherstone and
his colleagues reasoned that adult fly brains have dual-track sensory circuits,
one that triggers heterosexual behavior, the other homosexual. When GB
suppresses glutamatergic synapses, the homosexual circuit is blocked.
Meanwhile, a new book by a British anthropologist is likely to be equally
controversial. Desmond Morris, who previously wrote The Naked Ape, claims in his
new book The Naked Man that some men are gay because they failed to break the
'boys together' stage of childhood. That claims Morris results in gay men being
more playful and experimental and leads to gays being more artistic. "Gays have
in general made a disproportionately greater contribution to life than nongays,"
he writes, pointing to gays like Socrates, Leonardo da Vinci, Tchaikovsky, Cole
Porter and Oscar Wilde.
قبل از اینکه راه بیفتید و بگید که داروی همجنس گرایی و دگر جنس گرایی کشف شده بدانید که "این تحقیق در مگس بوده نه انسان" !
مقاله ای آمده از دانشگاه Illinois در شیکاگو و محققی به نام David Featherstone ادعا کرده که همجنس گرایی در یک نوع مگس به وسیله تنظیم کننده سیناپسی که قبلا ناشناخته بوده کنترل میشه. محقان این پروژه ادعا کردند که با استفاده از دارو و تغییرات ژنتیکی این تنظیم کننده سیناپسی را میتوانند دست کاری کنند و همجنس گرایی را مانند یک سوئیچ در این نوع مگس خاموش و روشن کنند. همچنین این محققان ژنی را در این مگس به نام genderblind کشف
کردند که آن را به اختصار GB نام گذاشتند،
همچنین مشاهده کردند که نوعی تحول در ژن GB این مگس را دو جنس گرا میکند.
Fruit Fly Homosexuality Study
Likely To Prove Controversial
by 365Gay.com Newscenter Staff
Posted: December 10, 2007 - 8:00 am ET
(Chicago,
Illinois) While the biological basis for homosexuality remains a mystery, a
team of neurobiologists says it may be closer to an answer.
The team led by University of
Illinois at Chicago researcher David Featherstone says it has discovered that
sexual orientation in fruit flies is controlled by a previously unknown
regulator of synapse strength.
Armed with this knowledge, the researchers claim they were able to use either
genetic manipulation or drugs to turn the flies' homosexual behavior on and off
within hours.The research will appear in the January issue of Nature
Neuroscience the university said.
Featherstone, associate professor of biological sciences at UIC, and his
coworkers discovered a gene in fruit flies they called "genderblind," or GB. A
mutation in GB turns flies bisexual.Featherstone found the gene interesting
initially because it has the unusual ability to transport the neurotransmitter
glutamate out of glial cells -- cells that support and nourish nerve cells but
do not fire like neurons do. Previous work from his laboratory showed that
changing the amount of glutamate outside cells can change the strength of nerve
cell junctions, or synapses, which play a key role in human and animal behavior.
But the GB gene became even more interesting when post-doctoral researcher Yael
Grosjean noticed that all the GB mutant male flies were courting other males.
"It was very dramatic," said Featherstone. The GB mutant males, he said, treated
other males exactly the same way nonmutant male flies would treat a female. They
even attempted copulation Featherstone said. Other genes that alter sexual
orientation have been described, but most just control whether the brain
develops as genetically male or female. It's still unknown why a male brain
chooses to do male things and a female brain does female things. The discovery
of GB provided an opportunity to understand why males choose to mate with
females. "Based on our previous work, we reasoned that GB mutants might show
homosexual behavior because their glutamatergic synapses were altered in some
way," said Featherstone. Specifically, the GB mutant synapses might be stronger.
"Homosexual courtship might be sort of an 'overreaction' to sexual stimuli," he
explained. To test this, he and his colleagues genetically altered synapse
strength independent of GB, and also fed the flies drugs that can alter synapse
strength. As predicted, they were able to turn fly homosexuality on and off --
and within hours."It was amazing. I never thought we'd be able to do that sort
of thing, because sexual orientation is supposed to be hard-wired," he said.
"This fundamentally changes how we think about this behavior." Featherstone and
his colleagues reasoned that adult fly brains have dual-track sensory circuits,
one that triggers heterosexual behavior, the other homosexual. When GB
suppresses glutamatergic synapses, the homosexual circuit is blocked.
Meanwhile, a new book by a British anthropologist is likely to be equally
controversial. Desmond Morris, who previously wrote The Naked Ape, claims in his
new book The Naked Man that some men are gay because they failed to break the
'boys together' stage of childhood. That claims Morris results in gay men being
more playful and experimental and leads to gays being more artistic. "Gays have
in general made a disproportionately greater contribution to life than nongays,"
he writes, pointing to gays like Socrates, Leonardo da Vinci, Tchaikovsky, Cole
Porter and Oscar Wilde.
مطلب را به بالاترین بفرستید:
Hamjensgera- مدیر
- تعداد پستها : 181
Age : 41
محل سکونت : Tehran
Registration date : 2007-10-04
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